Peer reviewed publications


Hu Y, Schmitt-Engel C, Schwirz J, Stroehlein N, Richter T, Majumdar U, Bucher G (2018) A morphological novelty evolved by co-option of a reduced gene regulatory network and gene recruitment in a beetle. Proc R Soc B. 285:20181373.

Ansari* S, Troelenberg*, Dao, Richter, Gregor Bucher# and Martin Klingler# (2018) Double abdomen in a short-germ insect: Zygotic control of axis formation revealed in the beetle Tribolium castaneum. PNAS

Dönitz J., Gerischer L, Hahnke S, Pfeiffer S, Bucher G. (2018) Expanded and updated data and a query pipeline for iBeetle-Base. Nucleic Acids Res. 4;46(D1):D831-D835. doi: 10.1093/nar/gkx984.


Kitzmann P, Weißkopf M, Schacht MI, Bucher G foxQ2 has a key role in anterior head and central brain patterning in insects. Development 2017 : doi: 10.1242/dev.147637

Schwager EE, Sharma PP, Clarke T, Leite DJ, Wierschin T, Pechmann M, et al. The house spider genome reveals an ancient whole-genome duplication during arachnid evolution. BMC Biol. 2017;15:62.

Hahn N, Knorr DY, Liebig J, Wüstefeld L, Peters K, Büscher M, Bucher, G, Ehrenreich H, Heinrich, R The Insect Ortholog of the Human Orphan Cytokine Receptor CRLF3 Is a Neuroprotective Erythropoietin Receptor. Front. Mol. Neurosci. 2017;10


Koniszewski*, NDB, Kollmann* M, Bigham M, Farnworth M, He B, Büscher M, Hütteroth W, Binzer M, Schachtner J, Bucher, G. The insect central complex as model for heterochronic brain development-background, concepts, and tools. Dev. Genes Evol. 2016;226:209-19.


Siemanowski, J., Richter, T., Dao, V. A. & Bucher, G. Notch signaling induces cell proliferation in the labrum in a regulatory network different from the thoracic legs. Dev. Biol. 408, 164-177 (2015).

Ulrich, J., Dao, V.A., Majumdar, U., Schmitt-Engel, C., Schwirz, J., Schultheis, D., Ströhlein, N., Troelenberg, N., Grossmann, D., Richter, T., Dönitz, J., Gerischer, L., Leboulle, G., Vilcinskas, A., Stanke, M., Bucher, G., (2015). Large scale RNAi Screen in Tribolium reveals novel Target Genes for Pest Control and the Proteasome as Prime Target. BMC Genomics.

Schmitt-Engel, C., Schultheis, D., Schwirz, J., Ströhlein, N., Troelenberg, N., Majumdar, U., Dao, V.A., Grossmann, D., Richter, T., Tech, M., Dönitz, J., Gerischer, L., Theis, M., Schild, I., Trauner, J., Koniszewski, N.D.B., Küster, E., Kittelmann, S., Hu, Y., Lehmann, S., Siemanowski, J., Ulrich, J., Panfilio, K.A., Schröder, R., Morgenstern, B., Stanke, M., Buchhholz, F., Frasch, M., Roth, S., Wimmer, E.A., Schoppmeier*, M., Klingler*, M., Bucher*, G., (2015). The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology. Nat. Commun. 6, 7822. doi:10.1038/ncomms8822 Highligthed in Science Editor´s choice

Dönitz, J., Schmitt-Engel, C., Grossmann, D., Gerischer, L., Tech, M., Schoppmeier, M., Klingler, M. and Bucher, G. (2015). iBeetle-Base: a database for RNAi phenotypes in the red flour beetle Tribolium castaneum. Nucleic Acids Res. gku1054.


Oberhofer, G., Grossmann, D., Siemanowski, J. L., Beissbarth, T. and Bucher, G. (2014). Wnt/b-catenin signaling integrates patterning and metabolism of the insect growth zone. Development dev.112797.


Dönitz J, Grossmann D, Schild I, Schmitt-Engel C, Bradler S, Prpic NM, Bucher G (2013) TrOn: An Anatomical Ontology for the Beetle Tribolium castaneum PlosOne 8:7

Peel A, Grossmann D, Schanda J, Ruge F, Oberhofer G, Schinko JB, Gilles A, Klingler M, Bucher G (2013) Tc-knirps plays different roles in the specification of antennal and mandibular parasegment boundaries and is regulated by a pair-rule gene in the beetle Tribolium castaneum BMC Dev Biol 13:25

Kittelmann S, Ulrich J, Posnien N, Bucher G (2013) Changes in anterior head patterning underlie the evolution of long germ embryogenesis Dev Biol 374(1):174-84

Kitzmann P, Schwirz J, Schmitt-Engel C, Bucher G. (2013) RNAi phenotypes are influenced by the genetic background of the injected strain BMC Genomics 14:5


Schinko JB, Hillebrand K, Bucher G. (2012) Heat shock-mediated misexpression of genes in the beetle Tribolium castaneum. Dev Genes Evol. 2012 Sep7.(5):287-98.

Fu J, Posnien N, Bolognesi R, Fischer TD, Rayl P, Oberhofer G, Kitzmann P, Brown SJ, Bucher G. (2012) Asymmetrically expressed axin required for anterior development in Tribolium. PNAS 109(20):7782-6.


Posnien, N., Koniszewski, N. D. B., Hein, H. and Bucher, G. (2011). Candidate Gene Screen in the red flour beetle Tribolium Reveals six3 as Ancient Regulator of Anterior Median Head and Central Complex Development. Plos Genet 2011

N Posnien, N Koniszewski, G Bucher: Insect Tc-six4 marks a unit with similarity to vertebrate placodes. Dev Biol


Posnien, N. and Bucher, G. (2010). Formation of the insect head involves lateral contribution of the intercalary segment, which depends on Tc-labial function. Dev Biol. 338:107-16.

Schinko, M Weber, I Viktorinova, A Kiupakis, M Averof, M Klingler, EA Wimmer, G Bucher: Functionality of the GAL4/UAS system in Tribolium requires the use of endogenous core promoters. BMC Dev Biol 2010, 10:53.

Steinmetz, R Urbach, N Posnien, J Eriksson, RP Kostyuchenko, C Brena, K Guy, M Akam*, G Bucher*, D Arendt*: Six3 demarcates the anterior-most developing brain region in bilaterian animals. Evodevo 2010, 1:14.


Trauner, J., Schinko, J., Lorenzen, M. D., Shippy, T. D., Wimmer, E. A., Beeman, R. W., Klingler, M., Bucher, G. and Brown, S. J. (2009). Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps. BMC Biol 7:73.

Posnien, F Bashasab, G Bucher (2009) The insect upper lip (labrum) is a nonsegmental appendage-like structure. Evol Dev 11:479-487.

Yang X, M Weber, N Zarinkamar, N Posnien, F Friedrich, B Wigand, R Beutel, WG Damen, G Bucher, M Klingler, Friedrich, M (2009): Probing the Drosophila retinal determination gene network in Tribolium (II): The Pax6 genes eyeless and twin of eyeless. Dev Biol 333:215-27.

Kittelmann, M., Schinko, J. B., Winkler, M., Bucher, G., Wimmer, E. A. and Prpic, N. M. (2009). Insertional mutagenesis screening identifies the zinc finger homeodomain 2 (zfh2) gene as a novel factor required for embryonic leg development in Tribolium castaneum. Dev Genes Evol. 2009, 219:399-407.


Tomoyasu, Y., Miller, S.C., Tomita, S. Schoppmeier, M., Grossmann, D., Bucher, G. (2008) Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium. Genome Biol 9:1, R10

Tribolium Genome Sequencing Consortium# (2008) The first genome sequence of a beetle, Tribolium castaneum, a model for insect development and pest biology. nature 452, 949-55
# mentioned as one of twelve analysis leaders

Cerny, A., Grossmann, D., Bucher*, G. Klingler*, M. (2008) The Tribolium ortholog of knirps and knirps-related is crucial for head segmentation but plays a minor role during abdominal patterning. Dev Biol 321(1):284-94

Schinko, J.B., Kreuzer, N., Offen, N., Posnien, N., Wimmer, E., Bucher, G. (2008) Diverged function of Tribolium orthodenticle, empty-spiracles and buttonhead in head patterning. Dev Biol 317, 600-613

Witek A, Herlyn H, Meyer A, Boell L, Bucher G, Hankeln T. (2008) EST based phylogenomics of Syndermata questions monophyly of Eurotatoria. BMC Evol Biol. 8(1):345.

Boell, L., Bucher, G. (2008) Whole mount in situ hybridization in the Rotifer Brachionus plicatilis representing a basal branch of lophotrochozoans. Dev Genes Evol 8(8):445-51

until 2007

Wohlfrom, H., Klingler, M. and Bucher, G. (2006). knödel is a gene involved in segment maintenance in Tribolium castaneum (Coleoptera). MOD

Cerny*, A. C., Bucher*, G., Schroder, R. and Klingler, M. (2005). Breakdown of abdominal patterning in the Tribolium Kruppel mutant jaws. Development 132, 5353-63.

Bucher, G. and Klingler, M. (2005). Tribolium mae expression suggests roles in terminal and midline patterning and in the specification of mesoderm. Dev Genes Evol 215, 478-481.

Bucher*, G., Farzana*, L., Brown, S. J. and Klingler, M. (2005). Anterior localization of maternal mRNAs in a short germ insect lacking bicoid. Evol Dev 7, 142-9.

Bucher, G. and Klingler, M. (2004). Divergent segmentation mechanism in the short germ insect Tribolium revealed by giant expression and function. Development 131, 1729-40.

Bucher, G., Scholten, J. and Klingler, M. (2002). Parental RNAi in Tribolium (Coleoptera). Curr Biol 12, R85-6.

Berghammer, A., Bucher, G., Maderspacher, F. and Klingler, M. (1999). A system to efficiently maintain embryonic lethal mutations in the flour beetle Tribolium castaneum. Dev Genes Evol 209, 382-9.

Maderspacher*, F., Bucher*, G. and Klingler, M. (1998). Pair-rule and gap gene mutants in the flour beetle Tribolium castaneum. Dev Genes Evol 208, 558-68.


G. Bucher, Tribolium (2017), In Reference Module in Life Sciences, Elsevier, ISBN: 978-0-12-809633-8,

Ulrich J., Hu Y., Ansari S., Bucher, G. The red flour beetle - a new genetic model system for pest and vector control with the option of large-scale screening Nova Acta Leopoldina 2016;411:43-55.

Posnien, JB Schinko, S Kittelmann, G Bucher: (2010) Genetics, development and composition of the insect head--a beetle's view. Arthropod Struct Dev 2010, 39:399-410. (review)

Non peer review publications

J Schinko, N Posnien, S Kittelmann, N Koniszewski, G Bucher (2009): Single and Double Whole-Mount In Situ Hybridization in Red Flour Beetle (Tribolium) Embryos. Cold Spring Harbor Protocols 2009,:pdb.prot5258-.

N Posnien, JB Schinko, D Grossmann, TD Shippy, B Konopova, G Bucher (2009) RNAi in the Red Flour Beetle (Tribolium). Cold Spring Harb. Protoc. 2009, doi:10.1101/pdb.prot5256.

SJ Brown, TD Shippy, S Miller, R Bolognesi, RW Beeman, MD Lorenzen, G Bucher, EA Wimmer, M Klingler (2009) The Red Flour Beetle, Tribolium castaneum (Coleoptera): A Model for Studies of Development and Pest Biology. Cold Spring Harbor Protocols 2009, :pdb.emo126-.

Bucher, G. and Wimmer, E. (2005). Beetle a-head. B.I.F. Futura 20, 164-169.

Wigand, B., Bucher, G. and Klingler, M. (1998). A simple whole mount technique for looking at Tribolium embryos. Tribolium Bulletin 38, 281-282.