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Contact

Dr. Ralf Heinrich

Dept. of Cellular Neurobiology

Schwann-Schleiden Research Center

Julia-Lermontova-Weg 3

37077 Göttingen

Phone: +49(0)551 / 39177958
Fax: +49(0)551 / 39177952
E-mail: rheinri1@gwdg.de

Publications in books and other print media

Heinrich R., Günther V., Miljus N. Erythropoietin-mediated neuroprotection in insects suggests a prevertebrate evolution of erythropoietin-like signaling. Vitamins & Hormones 105: 181-196, 2017

Hahn N., Heinrich R.  Neuroligine, synaptische Regulation und Sozialverhalten von Mensch und Fliege. Biospektrum 21: 476-479, 2015.

Heinrich R. Mechanical communication: producing sound and substrate vibrations. In: The Insects: Structure, Functions and Genetics Editors: R. F. Chapman, S. J. Simpson, S. E. Douglas, E. Bernays. Cambridge University Press, pp. 824-856, 2012.

Heinrich R., Ganter G.K. Nitric oxide/cyclic GMP signaling and insect behavior. In: Nitric Oxide Editors: Bruno Tota and Barry Trimmer; Adv Exp Biol 1:107-127, 2007

Winkler M., Deubzer H.E., Hoch M., Witt O., Heinrich R. Elektronenmikroskopische Untersuchung von Neuroblastomzellen nach Kultivierung auf lumoxTM multiwell Platten. Greiner Bio-ONE, 2007

Heinrich R. Vom Wasserklo des Konrad Lorenz zur Chemie des Verhaltens. Motivationsforschung an kleinen Hirnen. In: Gehirn und Verstehen. Georgia Augusta 2, pp. 68-75, 2003

Heinrich, R., Cromarty, S.I., Hörner, M. and Kravitz, E.A. Intrinsic properties of lobster amine-containing neurosecretory neurons: spontaneous activity and autoinhibition. In: The crustacean nervous system. Editor: K. Wiese; Springer, Berlin Heidelberg, pp. 173-185, 2002

Hörner, M., Heinrich, R. and Kravitz, E.A. Synaptic connectivity of amine-containing neurosecretory cells of lobsters: Inputs to 5HT- and OCT-containing neurons. In: The crustacean nervous system. Editor: K. Wiese; Springer, Berlin Heidelberg, pp. 156-172, 2002

Publications in peer reviewed journals

Hahn N., Knorr D.Y., Liebig J., Wüstefeld L., Peters K., Büscher M., Bucher G., Ehrenreich H., Heinrich R.  The insect orthologue of the human orphan cytokine receptor CRLF3 is a neuroprotective erythropoietin receptor in insects. Frontiers in Molecular Neuroscience 10: 223, 2017

Corthals K. Heukamp A.S., Kossen R., Großhennig I., Hahn N., Göpfert M., Heinrich R., Geurten B.R.   Neuroligins Nlg2 and Nlg4 affect social behaviour in Drosophila melanogasterFrontiers in Psychiatry 8: 113, 2017

Bhavsar M.B.,  Stumpner A., Heinrich R.  Brain regions for sound processing and song release in a small grasshopper. Journal of Insect Physiology 99: 15-24, 2017

Miljus N., Massih B., Weis M.A., Rison J.V., Bonnas C.B., Sillaber I., Ehrenreich H., Geurten B.R.H., Heinrich R.  Neuroprotection and endocytosis: erythropoietin receptors in insect nervous systems. Journal of Neurochemistry 141: 63-74, 2017

Versteven M., Vanden Broeck L., Geurten B., Zwarts L.,Decraecker L., Beelen M., Göpfert M.C., Heinrich R., Callaerts P. Hearing regulates Drosophila aggression. Proc Nat Acad Sci USA 114: 1958-1963, 2017

Faghihi F., Moustafa A.A., Heinrich R., Wörgötter F.  A computational model of conditioning inspired by Drosophila olfactory system. Neural Networks 87: 96-108, 2017

Bhavsar M.B., Heinrich R., Stumpner A. Multielectrode recordings in insect brains. Neuroscience Communications 1: e1088, 2016

Bhavsar M.B., Heinrich R., Stumpner A. Multielectrode recordings from auditory neurons in the brain of a small grasshopper. Journal of Neuroscience Methods, 256: 63-73, 2015.

Mitkowski M., Dahm L., Heinrich R., Monnheimer M., Gerhardt S., Stegmüller J., Hanisch U.K., Nave K.A., Ehrenreich H.  Erythropoietin dampens injury-induced microglial motility. Journal of Cerebral Blood Flow & Metabolism 35:1233-1236, 2015.

Miljus N., Heibeck S., Jarrar M., Micke M., Ostrowski D., Ehrenreich H.. Heinrich R.  Erythropoietin-mediated protection of insect brain neurons involves JAK and STAT but not PI3K transduction pathways. Neuroscience 258:218-227, 2014.

Hahn N., Geurten B., Gurvich A., Piepenbrock D., Kästner A., Zanini, D., Xing G., Xie W., Göpfert M.C., Ehrenreich H., Heinrich R.  Monogenic heritable autism gene neuroligin impacts Drosophila social behaviour. Behavioural Brain Research 252: 450-457, 2013

Kästner A., Grube S., El-Kordi A., Stepniak B., Friedrichs H., Sargin D., Schwitulla J., Begemann M., Giegling I., Miskowiak K., Sperling S., Hannke K., Ramin A., Heinrich R., Gefeller O., Nave K., Rujescu D., Ehrenreich H. Common variants of the genes encoding erythropoietin and its receptor modulate cognitive performance in schizophrenia.  Molecular Medicine 18: 1029-1040, 2012

Heinrich R., Kunst M., Wirmer A.  Reproduction-related sound production of grasshoppers regulated by internal state and actual sensory environment. Frontiers in Decision Neuroscience 6: 89, 2012.

Wirmer A., Bradler S., Heinrich R. Homology of insect corpora allata and vertebrate adenohypophysis? Arthropod Structure & Development  41: 409-417, 2012.

Ganter G.K., Desilets J.B., Davis-Knowlton J.A., Panaitiu A.E., Sweezy M., Adams A.M., Fisher E.A., O'Brien J.R.M., Kincaid K.M., Heinrich R.   Drosophila female precopulatory behavior is modulated by ecdysteroids. J Insect Physiol 58: 413-419, 2012  

Kunst M., Pförtner R., Aschenbrenner K., Heinrich R. Neurochemical architecture of the central complex related to its function in the control of grasshopper acoustic communication.  PLoS ONE 6(9): e25613, 2011

Ganter G. K., Panaitiu A. E. , Desilets J., Davis-Heim J., Fisher E. A., Tan L. C. H., Heinrich, R., Buchanan E. B., Brooks K. M., Kenney M. T., Verde M. G., Downey J., Adams A. M. Grenier J. S., Maddula S., Shah P., Kincaid, K. Drosophila male sexual behavior is modulated by the steroid hormone ecdysone. J Insect Physiol 57: 1179-1184, 2011

Ostrowski D., Ehrenreich H., Heinrich R.  Erythropoietin promotes survival and regeneration of insect neurons in vivo and in vitro. Neuroscience 188: 95-108, 2011

Johnsson T., Kravitz E. A., Heinrich R. Sound production during agonistic behaviour of male Drosophila melanogaster. Fly 5: 29-38, 2011

Wirmer A., Heinrich R. Nitric oxide/cGMP signaling in the corpora allata of female grasshoppers. J Insect Physiol  57: 94-107, 2011

Farca Luna A. J., Heinrich R., Reischig T. The circadian biology of the marbled crayfish. Frontiers in Bioscience E2(4): 1414-1431, 2010

Wirmer A., Faustmann M., Heinrich R. Reproductive behaviour of female Chorthippus biguttulus grasshoppers. J Insect Physiol 56: 745-753, 2010

Heck C., Kunst M., Härtel K., Hülsmann S., Heinrich R. In vivo labeling and in vitro characterisation of central complex neurons involved in the control of sound production. J Neuroscience Methods 183: 202-212, 2009

Gocht D., Wagner S., Heinrich R. Recognition, presence and survival of locust central nervous glia in situ and in vitro. Microscopy Research and Technique 72: 385-397, 2009

Farca Luna A.J., Hurtado-Zavala J.I., Heinrich R. Circadian regulation of agonistic behavior in groups of parthenogenetic marbled crayfish. Journal of Biological Rhythms 24: 64-72, 2009

Weinrich A., Kunst M., Wirmer A., Holstein G.R., Heinrich R. Suppression of grasshopper sound production by nitric oxide-releasing neurons of the central complex. J Comp Physiol A 194: 763-776, 2008

Deubzer H.E., Ehemann V., Westermann F., Heinrich R., Mechtersheimer G., Kulozik A.E., Schwab M., Witt O. Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin, suppresses the phenotype of neuroblastoma cells. Int J Cancer 122:1891-900, 2008

Hoffmann K., Wirmer A., Kunst M., Gocht D., Heinrich R. Muscarinic excitation in grasshopper song control circuits is limited by acetylcholinesterase activity. Zool Sci 24: 1028-1035, 2007

Gocht D., Heinrich R. Postactivation inhibition of spontaneously active neurosecretory neurons in the medicinal leech. J Comp Physiol A 193:347-361, 2007

Wenzel B., Kunst M., Günther C., Ganter G.K., Lakes-Harlan R., Elsner N., Heinrich R. Nitric oxide/cyclic GMP-signaling in the central complex of the grasshopper brain inhibits singing behavior. J Comp Neurol, 488: 129-139, 2005

Heinrich R. Impact of descending brain neurons on the control of stridulation, walking and flight in orthoptera. Microscopy Research and Technique 56: 292-301, 2002

Wenzel B., Elsner N. and Heinrich R. mAChRs in the grasshopper brain mediate excitation by activation of the AC/PKA and the PLC second-messenger pathways. J Neurophysiol 87: 876-888, 2002

Vedenina V.Yu., Heinrich R. and Elsner N. Pharmacological activation of stridulatory behaviour in the grasshopper Chorthippus albomarginatus (Orthoptera: Gomphocerinae). J Evol Biochem Physiol 37: 388-397, 2001

Heinrich R., Wenzel B. and Elsner N. A role for muscarinic excitation: Control of specific singing behavior by activation of the adenylate cyclase pathway in the brain of grasshoppers. Proc Nat Acad Sci USA 98: 9919-9923, 2001

Doernberg S.B., Cromarty S.I., Heinrich R., Beltz B.S. and Kravitz E.A. Agonistic behavior in naive juvenile lobsters depleted of serotonin by 5,7-dihydroxytryptamine. J Comp Physiol A 187: 91-103, 2001

Heinrich R., Wenzel B. and Elsner N. Pharmacological brain stimulation releases elaborate stridulatory behaviour in gomphocerine grasshoppers – conclusions for the organization of the central nervous system. J Comp Physiol A 187: 155-169, 2001

Heinrich R., Bräunig P., Walter I., Schneider H. and Kravitz E.A. Aminergic neuron systems of lobsters: Morphology and electrophysiology of octopamine-containing neurosecretory cells. J Comp Physiol A 186: 617-629, 2000

Heinrich R., Cromarty S.I., Hörner M., Edwards D.H. and Kravitz E.A. Autoinhibition of serotonin cells: an intrinsic regulatory mechanism sensitive to the pattern of usage of the cells. Proc Nat Acad Sci USA 96: 2473-2478, 1999

Ganter G.K., Heinrich R., Bunge R.P. and Kravitz E.A. Long-term culture of lobster central ganglia: expression of foreign genes in identified neurons. Biol Bull 197: 40-48, 1999

Lakes-Harlan R., Jacobs K., Heinrich R. Identification of auditory interneurons in situ and in vitro by tracer injection into an afferent neuropil. Naturwissenschaften 85, 240-243, 1998

Heinrich, R., Rozwod, K. and Elsner, N. Neuropharmacological evidence for inhibitory cephalic control mechanisms of stridulatory behaviour in grasshoppers. J Comp Physiol A 183, 389-399, 1998

Heinrich R., Jacobs K., Lakes-Harlan R. Tracing of a neuronal network in the locust by pressure injection of markers into a synaptic neuropil. J Neurosci Meth 80, 81-98, 1998

Heinrich, R., Hedwig, B. and Elsner, N. Cholinergic activation of stridulatory behaviour in the grasshopper Omocestus viridulus L. J Exp Biol 200, 1327-1337, 1997

Hedwig, B. and Heinrich, R. Identified descending brain neurons control different stridulatory motor patterns in an acridid grasshopper. J Comp Physiol A 180, 285-294, 1997

Heinrich, R. and Elsner, N. Central nervous control of hindleg coordination in stridulating grasshoppers. J Comp Physiol A 180, 257-269, 1997

Heinrich, R., Jahto, M. and Kalmring, K. Acoustic transmission characteristics of the tympanal tracheae of bushcrickets (Tettigoniidae). II: Comparative studies of the tracheae of seven species. J Acoust Soc Am 93, 3481-3489, 1993

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