Structure formation in early Drosophila embryos
Research topics
Epithelial morphogenesis and cell cycle switch
- Membrane and epithelial compartment formation
- Actin dynamics and Rho signalling
- Role of the slam RNA-protein complex
- Cell cycle control
Quantitative morphogenesis (Biomechanics)
- Nuclear ordering and cytoskeletal network dynamics
- Cell intercalation and junction dynamics
Size and form of the nucleus - Ageing
- Farnesylated nuclear lamina proteins
- Drosophila model for the Hutchinson-Gilford progeria (HGPS) and other laminopathies
- Lamina proteins in regeneration and proliferation of intestinal stem cells
Methods
- Drosophila genetics, embryology, adult ageing
- Molecular genetics
- Biochemistry
- Classical and quantitative microscopy and live imaging
- Micro-surgery with UV laser
- Computational image analysis
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